Early Detection of Pancreatic Cancer in Type 2 Diabetes Mellitus Patients
https://cesnet.zoom.us/j/92664747416
Using 1H NMR analysis of blood samples, it is possible to capture the concentration changes of individual metabolites caused by various diseases. Multidimensional statistics can then clearly distinguish samples of patients from samples of healthy individuals. In a pilot study, we were able to distinguish patients with pancreatic cancer from control individuals. In a subsequent study, we focused on the detection of pancreatic cancer in patients with type 2 diabetes. Based on the profiles of approximately 60 metabolites, it was possible to discriminate the cancer patients from those with diabetes. Successful discrimination subsequently allowed the creation of a predictive model for the classification of new diabetics according to the probability of future pancreatic cancer development or turning into stable type 2 diabetics.